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Home - Products - Antibody Drug Conjugates (ADC) - ADCs Linker/Click Chemistry - PC Biotin-PEG3-alkyne

PC Biotin-PEG3-alkyne

CAS No. 1869922-24-6

PC Biotin-PEG3-alkyne( —— )

Catalog No. M33453 CAS No. 1869922-24-6

PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PC Biotin-PEG3-alkyne
  • Note
    Research use only, not for human use.
  • Brief Description
    PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).
  • Description
    PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PC Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1869922-24-6
  • Formula Weight
    780.89
  • Molecular Formula
    C35H52N6O12S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CCCC(NCCOCCOCCOCCNC(CCCOC1=C(OC)C=C(C(OC(NCC#C)=O)C)C(N(=O)=O)=C1)=O)=O)[C@H]2[C@@]3([C@](CS2)(NC(=O)N3)[H])[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.?
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